Awarded Grants
Awarded Grants
Regulation of CDKL5 Function by Type I Interferons"
Josephine Thinwa, PhD
UT Southwestern Medical Center, USA
$150,000
Awardee: Josephine Thinwa, PhD
Institution: UT Southwestern Medical Center, USA
Award Amount: $150,000
Funding Period: May 1, 2025 - April 31, 2026
Development of a tau hyperphosphorylation assay in CDKL5 deficiency disorder iPSC-derived neurons
Jedd Hubbs, PhD
Boston Children's Hospital, USA
$149,050
Awardee: Jedd Hubbs, PhD
Institution: Boston Children's Hospital, USA
Award Amount: $149,050
Funding Period: May 1, 2025 - April 31, 2026
Exploiting microRNAs to disclose novel pathophysiological mechanisms, biomarkers and therapeutic approaches for CDKL5 deficiency disorder
Maurizio Giustetto, PhD
University of Torino, Italy
$134,300
Awardee: Maurizio Giustetto, PhD
Institution: University of Torino, Italy
Award Amount: $134,300
Funding Period: May 1, 2025 - April 31, 2026
Preclinical Investigations Of Proteasome and Lysosome Inhibitors In CDKL5 Deficient Mice"
James Eubanks, PhD
University Health Network - Krembil Research Institute, Canada
$147,896
Awardee: James Eubanks, PhD
Institution: University Health Network - Krembil Research Institute, Canada
Award Amount: $147,896.00
Funding Period: May 1, 2025 - April 31, 2026
Profiling CDKL5 signaling landscape at the synapses
W. Andy Tao
Purdue University
$150,000
Awardee: W. Andy Tao
Institution: Purdue University
Award Amount: $150,000
Funding Period: May 1, 2024 - April 31, 2025
CDKL5 in Biomolecular Condensates and its Role in CDD Pathophysiology
Keren Lasker
The Scripps Research Institute
$150,000
Awardee: Keren Lasker
Institution: The Scripps Research Institute
Award Amount: $150,000
Funding Period: May 1, 2024 - April 31, 2025
Cortical Visual Impairment in CDKL5 Deficiency: Dissecting the Link between Functional Deficits and Molecular Mechanisms
Jacque Pak Kan Ip
The Chinese University of Hong Kong
$150,000
Awardee: Jacque Pak Kan Ip
Institution: The Chinese University of Hong Kong
Award Amount: $150,000
Funding Period: May 1, 2024 - April 31, 2025
Looking for differences: in vitro isolation of hCDKL5-specific antibody fragments and set-up of a method to quantify hCDKL5 and possibly distinguish between its isoforms.
Ario de Marco
University of Nova Gorica
$150,000
Awardee: Ario de Marco
Institution: University of Nova Gorica
Award Amount: $150,000
Funding Period: May 1, 2024 - April 31, 2025
Integrating Experimental and Computational Approaches to Unravel the Neurophysiological Basis of CDKL5 Deficiency Disorder
Roy Ben-Shalom
UC Davis
$148,442
Awardee: Roy Ben-Shalom
Institution: UC Davis
Award Amount: $148,442
Funding Period: May 1, 2024 - April 31, 2025
Assessment of the therapeutic potential of TATk-hCDKL5 isoform 1 and 2 produced in recombinant Antarctic Pseudoalteromonas haloplanktis TAC125
Maria Luisa Tutino, PhD
University Federico II of Naples
$149,985.00
Awardee: Maria Luisa Tutino, PhD
Institution: University Federico II of Naples
Award Amount: $149,985.00
Funding Period: May 1, 2023 - April 31, 2024
Therapeutic potential of Ca2.3 inhibitors in CDD mouse and human models
Marisol Sampedro Castanedo, PhD
Francis Crick Institute
$149,942.00
Awardee: Marisol Sampedro Castanedo, PhD
Institution: Francis Crick Institute
Award Amount: $149,942.00
Funding Period: May 1, 2023 - April 31, 2024
New Drosophila models of CDD
Maximo Ibo Galindo
Centro de Investigación Príncipe Felipe
$148,950.00
Awardee: Maximo Ibo Galindo, PhD
Institution: Centro de Investigación Príncipe Felipe
Award Amount: $148,950.00
Funding Period: May 1, 2023 - April 31, 2024
Utilizing patient iPSC-derived neurons to determine the functional consequences of longer cilia in CDKL5 Deficiency Disorder (CDD)
Mustafa Sahin, MD PhD
Boston Children’s Hospital
$149,241
Awardee: Mustafa Sahin, MD PhD
Institution: Boston Children’s Hospital
Award Amount: $149,241
Funding Period: May 1, 2022 - April 31, 2023
Computational drug repurposing for CDKL5 Deficiency Disorder
Diego Di Bernardo, PhD
Telethon Institute of Genetics and Medicine
$150,000
Awardee: Diego Di Bernardo, PhD
Institution: Telethon Institute of Genetics and Medicine
Award Amount: $150,000
Funding Period: May 1, 2022 - April 31, 2023
Rescuing functional defects in a zebrafish model of CDKL5 deficiency: Contribution to the identification of therapeutic target
M. Leonor Cancela, PhD
University of Algarve
$141,338
Awardee: M. Leonor Cancela, PhD
Institution: University of Algarve
Award Amount: $141,338
Funding Period: May 1, 2022 - April 31, 2023
A functional genomics approach to dissect the molecular bases of CDKL5 Deficiency Disorder
Davide Cacchiarelli, PhD
Telethon Institute of Genetics and Medicine
$150,000
Awardee: Davide Cacchiarelli, PhD
Institution: Telethon Institute of Genetics and Medicine
Award Amount: $150,000
Funding Period: May 1, 2022 - April 31, 2023
Hematopoietic stem cell gene therapy as a therapeutic approach for CDKL5 Deficiency Disorder
Joseph Anderson, PhD
University of California, Davis
$150,000
Awardee: Joseph Anderson, PhD
Institution: University of California, Davis
Award Amount: $150,000
Funding Period: May 1, 2022 - April 31, 2023
ASO therapy in CDKL5 deficiency disorder
Michela Fagiolini, PhD
Boston Children's Hospital
$150,000
Awardee: Michela Fagiolini, PhD
Institution: Boston Children's Hospital
Award Amount: $150,000
Funding Period: May 1, 2021 - April 31, 2022
Comparison of Brain Biodistribution of Two CDKL5 Gene Therapy Vector Leads
Dolan Sondhi, PhD
Weill Cornell Medicine
$150,000
Awardee: Dolan Sondhi, PhD
Institution: Weill Cornell Medicine
Award Amount: $150,000
Funding Period: May 1, 2021 - April 31, 2022
Advancing a mosaic CDKL5 zebrafish model for high-throughput screening approaches
Christopher McGraw, MD, PhD
Boston Children's Hospital
$150,000
Awardee: Christopher McGraw, MD, PhD
Institution: Boston Children's Hospital
Award Amount: $150,000
Funding Period: May 1, 2021 - April 31, 2022